{"id":7128,"date":"2016-09-07T21:31:47","date_gmt":"2016-09-07T20:31:47","guid":{"rendered":"http:\/\/www.theoillamp.co.uk\/?p=7128"},"modified":"2016-09-07T21:32:27","modified_gmt":"2016-09-07T20:32:27","slug":"particulates-alzheimers-disease","status":"publish","type":"post","link":"https:\/\/www.theoillamp.co.uk\/?p=7128","title":{"rendered":"Particulates and Alzheimer\u2019s disease"},"content":{"rendered":"

\"boiler\"<\/a>There could be a link between particulates and Alzheimer\u2019s disease.\u00a0 This is according to a study just released which has found particulates in the brains of people who have died from this disease.\u00a0 This adds to the list of problems that particulates cause such as lung disease and strokes.\u00a0 Alzheimer\u2019s disease is of course complex and a number of agents have been implicated as its cause.\u00a0 Also just just because there is correlation does not mean there is causation.\u00a0 These particles contain small amounts of metals (magnetite).<\/p>\n

There is some logic to this scientifically.\u00a0 In Alzheimer\u2019s disease a protein amyloid-\u03b2 forms abnormal filaments in the brain.\u00a0 These aggregate and damage the brain’s neural pathways.\u00a0 The expression of the amyloid-\u03b2 is partially controlled by metals such as iron, zinc and copper.\u00a0 In addition iron and copper can undergo a series of oxidation and reduction reactions with hydrogen peroxide<\/a>.\u00a0 Hydrogen peroxide is produced by the body as a natural product of metabolism.\u00a0 When it reacts with these metals it forms free radicals which are molecules with a single unpaired electron.\u00a0 Chemically this is highly unstable and such groups can react very rapidly with almost any molecules in the body causing great damage.\u00a0 Living organisms that are aerobic have evolved a series of enzymes that break the peroxide down very rapidly.\u00a0 The problem is if large amounts of metals become embedded then this system is likely to be overwhelmed.<\/p>\n

A large number of other factors have been implicated in this terrible disease such as genetic factors and processes related to ageing.\u00a0 Nevertheless there is a a lesson here that we should cut the causes of particulates which includes all combustion processes down for our own good, the worst offenders being cars and coal fired power stations.<\/p>\n

Link to the paper here<\/a>.<\/p>\n

Neil<\/p>\n","protected":false},"excerpt":{"rendered":"

There could be a link between particulates and Alzheimer\u2019s disease.\u00a0 This is according to a study just released which has found particulates in the brains of people who have died from this disease.\u00a0 This adds to the list of problems … Continue reading →<\/span><\/a><\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_exactmetrics_sitenote_active":false,"_exactmetrics_sitenote_note":"","_exactmetrics_sitenote_category":0,"footnotes":""},"categories":[106,28,1],"tags":[],"class_list":["post-7128","post","type-post","status-publish","format-standard","hentry","category-materials","category-other","category-uncategorized"],"yoast_head":"\nParticulates and Alzheimer\u2019s disease - The oil lamp - shining God's light on peak oil<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.theoillamp.co.uk\/?p=7128\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/www.theoillamp.co.uk\/?p=7128\",\"url\":\"https:\/\/www.theoillamp.co.uk\/?p=7128\",\"name\":\"Particulates and Alzheimer\u2019s disease - 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